|
KMID : 0191120080230010111
|
|
Journal of Korean Medical Science
2008 Volume.23 No. 1 p.111 ~ p.116
|
|
|
Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study
|
|
Lee Jung-Ryeol
Jee Byung-Chul
Suh Chang-Suk
Ku Seung-Yup
Kim Seok-Hyun
Kim Ki-Chul
|
|
|
Abstract
|
|
|
|
The purpose of this study was to evaluate the outcomes of various methods of multifetal pregnancy reduction (MFPR) and to determine which method produces better outcomes. One hundred and forty-eight patients with multiple pregnancies resulting from assisted reproduction programs and underwent MFPR were included. According to the use of potassium chloride (KCl), patients were divided into ’KCl’, and ’non- KCl’ groups, and based on gestational age at the time of procedures, patients were divided into ’Early’ (before 8 weeks of gestation) and ’Late’ (at 8 weeks or later) groups. Firstly, to clarify the effect of each component of MFPR procedure, data were analyzed between ’KCl’ and ’non-KCl’ groups, and between ’Early’ and ’Late’ groups with adjustments. Secondly, comparison between ’Early, non-KCl’ and ’Late, KCl’ groups was performed to evaluate the combinative effect of both components. Non-KCl groups showed a significantly higher take-home-baby rate, and lower risk of extreme prematurity and preterm premature rupture of membranes (PPROM) than KCl groups. Early groups showed a lower immediate loss rate than Late groups. As compared with ’Late, KCl’ group, ’Early, non-KCl’ group was superior in terms of immediate loss, pregnancy loss, take-home-baby, and PPROM rates. Our data suggest that the ’Early, non-KCl’ method may be a better option for MFPR.
|
|
|
KEYWORD
|
|
|
Pregnancy Reduction, Multifetal, Pregnancy, Multiple, Reproductive Technology, Assisted, Pregnancy
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|
|